Lab of Molecular Imaging and Stem Cell Therapy

Nankai University School of Medicine
Tianjin 300071
China

http://www.researcherid.com/rid/G-3118-2010

(Full papers can be found @ https://www.researchgate.net/profile/Zongjin_Li3/publications)

Hou, H.; Zhang, L.; Duan, L.; Liu, Y.; Han, Z.; Li, Z.; Cao, X. Spatio-Temporal Metabolokinetics and Efficacy of Human Placenta-Derived Mesenchymal Stem/Stromal Cells on Mice with Refractory Crohn’s-like Enterocutaneous Fistula. Stem Cell Reviews and Reports 2020. in press
Zhang, K.; Chen, X.; Li, H.; Feng, G.; Nie, Y.; Wei, Y.; Li, N.; Han, Z.; Han, Z.; Kong, D.; Guo, Z.; Zhao, Q.; Li, Z. A Nitric Oxide-Releasing Hydrogel for Enhancing the Therapeutic Effects of Mesenchymal Stem Cell Therapy for Hindlimb Ischemia. Acta Biomaterialia 2020, 113, 289-304.
Zhang, K.; Chen, S.; Sun, H.; Wang, L.; Li, H.; Zhao, J.; Zhang, C.; Li, N.; Guo, Z.; Han, Z.; Han, Z. C.; Zheng, G.; Chen, X.; Li, Z. In vivo two-photon microscopy reveals the contribution of Sox9+ cell to kidney regeneration in a mouse model with extracellular vesicle treatment. J Biol Chem 2020, 295, 12203-12213.
Yao, Y.; Yang, L.; Feng, L. F.; Yue, Z. W.; Zhao, N. H.; Li, Z.; He, Z. X. IGF-1C domain-modified hydrogel enhanced the efficacy of stem cells in the treatment of AMI. Stem Cell Res Ther 2020, 11, 136.
Yao, J.; Chen, N.; Wang, X.; Zhang, L.; Huo, J.; Chi, Y.; Li, Z.; Han, Z. Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice. Stem Cells Int 2020, 2020, 6489396.
Wang, H.; Shang, Y.; Chen, X.; Wang, Z.; Zhu, D.; Liu, Y.; Zhang, C.; Chen, P.; Wu, J.; Wu, L.; Kong, D.; Yang, Z.; Li, Z.; Chen, X. Delivery of MSCs with a Hybrid beta-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy. Int J Nanomedicine 2020, 15, 4311-4324.
Midgley, A. C.; Wei, Y.; Li, Z.; Kong, D.; Zhao, Q. Nitric-Oxide-Releasing Biomaterial Regulation of the Stem Cell Microenvironment in Regenerative Medicine. Adv Mater 2020, 32, e1805818.
Liu, Y.; Cui, J.; Wang, H.; Hezam, K.; Zhao, X.; Huang, H.; Chen, S.; Han, Z.; Han, Z. C.; Guo, Z.; Li, Z. Enhanced therapeutic effects of MSC-derived extracellular vesicles with an injectable collagen matrix for experimental acute kidney injury treatment. Stem Cell Res Ther 2020, 11, 161.
Li, Q.; Cui, J.; Huang, H.; Yue, Z.; Chang, Y.; Li, N.; Han, Z.; Han, Z. C.; Guo, Z.; Li, Z. IGF-1C domain-modified chitosan hydrogel accelerates cutaneous wound healing by promoting angiogenesis. Future Med Chem 2020, 12, 1239-1251.
Lei, X.; He, N.; Zhu, L.; Zhou, M.; Zhang, K.; Wang, C.; Huang, H.; Chen, S.; Li, Y.; Liu, Q.; Han, Z.; Guo, Z.; Han, Z.; Li, Z. Mesenchymal Stem Cells Derived Extracellular Vesicles Attenuate Radiation-Induced Lung Injury via miRNA-214-3p. Antioxidants & Redox Signaling 2020.
Duan, L.; Huang, H.; Zhao, X.; Zhou, M.; Chen, S.; Wang, C.; Han, Z.; Han, Z.-C.; Guo, Z.; Li, Z.; Cao, X. Extracellular vesicles derived from human placental mesenchymal stem cells alleviate experimental colitis in mice by inhibiting inflammation and oxidative stress. International Journal of Molecular Medicine 2020, 46, 1551-1561..
Cao, X.; Duan, L.; Hou, H.; Liu, Y.; Chen, S.; Zhang, S.; Liu, Y.; Wang, C.; Qi, X.; Liu, N.; Han, Z.; Zhang, D.; Han, Z.-C.; Guo, Z.; Zhao, Q.; Li, Z. IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE2-mediated M2 macrophage polarization. Theranostics 2020, 10, 7697-7709.
Zhao, X.; Cui, K.; Li, Z. The role of biomaterials in stem cell-based regenerative medicine. Future Med Chem 2019, 11, 1777-1790.
Zhao, S.; Xu, J.; Liu, S.; Cui, K.; Li, Z.; Liu, N. Dppa3 in pluripotency maintenance of ES cells and early embryogenesis. J Cell Biochem 2019, 120, 4794-4799.
Zhao, Q.; Zhang, L.; Wei, Y.; Yu, H.; Zou, L.; Huo, J.; Yang, H.; Song, B.; Wei, T.; Wu, D.; Zhang, W.; Zhang, L.; Liu, D.; Li, Z.; Chi, Y.; Han, Z.; Han, Z. Systematic comparison of hUC-MSCs at various passages reveals the variations of signatures and therapeutic effect on acute graft-versus-host disease. Stem Cell Res Ther 2019, 10, 354.
Zhao, N.; Yue, Z.; Cui, J.; Yao, Y.; Song, X.; Cui, B.; Qi, X.; Han, Z.; Han, Z. C.; Guo, Z.; He, Z. X.; Li, Z. IGF-1C domain-modified hydrogel enhances therapeutic potential of mesenchymal stem cells for hindlimb ischemia. Stem Cell Res Ther 2019, 10, 129.
Zhang, Y.; Xu, J.; Liu, S.; Lim, M.; Zhao, S.; Cui, K.; Zhang, K.; Wang, L.; Ji, Q.; Han, Z.; Kong, D.; Li, Z.; Liu, N. Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells. Theranostics 2019, 9, 6976-6990.
Zhang, Y.; Wang, D.; Xu, J.; Wang, Y.; Ma, F.; Li, Z.; Liu, N. Stat3 activation is critical for pluripotency maintenance. J Cell Physiol 2019, 234, 1044-1051.
Zhang, K.; Wang, C.; Wang, R.; Chen, S.; Li, Z. Dual Bioluminescence Imaging of Tumor Progression and Angiogenesis. JoVE 2019, e59763.
Zhao, X.; Cui, K.; Li, Z. The role of biomaterials in stem cell-based regenerative medicine. Future Med Chem 2019, 11, 1777-1790.
Zhao, S.; Xu, J.; Liu, S.; Cui, K.; Li, Z.; Liu, N. Dppa3 in pluripotency maintenance of ES cells and early embryogenesis. J Cell Biochem 2019, 120, 4794-4799.
Zhao, Q.; Zhang, L.; Wei, Y.; Yu, H.; Zou, L.; Huo, J.; Yang, H.; Song, B.; Wei, T.; Wu, D.; Zhang, W.; Zhang, L.; Liu, D.; Li, Z.; Chi, Y.; Han, Z.; Han, Z. Systematic comparison of hUC-MSCs at various passages reveals the variations of signatures and therapeutic effect on acute graft-versus-host disease. Stem Cell Res Ther 2019, 10, 354.
Zhao, N.; Yue, Z.; Cui, J.; Yao, Y.; Song, X.; Cui, B.; Qi, X.; Han, Z.; Han, Z. C.; Guo, Z.; He, Z. X.; Li, Z. IGF-1C domain-modified hydrogel enhances therapeutic potential of mesenchymal stem cells for hindlimb ischemia. Stem Cell Res Ther 2019, 10, 129.
Zhang, Y.; Xu, J.; Liu, S.; Lim, M.; Zhao, S.; Cui, K.; Zhang, K.; Wang, L.; Ji, Q.; Han, Z.; Kong, D.; Li, Z.; Liu, N. Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells. Theranostics 2019, 9, 6976-6990.
Zhang, Y.; Wang, D.; Xu, J.; Wang, Y.; Ma, F.; Li, Z.; Liu, N. Stat3 activation is critical for pluripotency maintenance. J Cell Physiol 2019, 234, 1044-1051.
Zhang, K.; Wang, C.; Wang, R.; Chen, S.; Li, Z. Dual Bioluminescence Imaging of Tumor Progression and Angiogenesis. JoVE 2019, e59763.
Wei, Y.; Hou, H.; Zhang, L.; Zhao, N.; Li, C.; Huo, J.; Liu, Y.; Zhang, W.; Li, Z.; Liu, D.; Han, Z.; Zhang, L.; Song, B.; Chi, Y.; Han, Z. JNKi- and DAC-programmed mesenchymal stem/stromal cells from hESCs facilitate hematopoiesis and alleviate hind limb ischemia. Stem Cell Res Ther 2019, 10, 186.
Wang, Y.; Liu, W.; Yuan, B.; Yin, X.; Li, Y.; Li, Z.; Cui, J.; Yuan, X.; Li, Y. The Application of Methylprednisolone Nanoscale Zirconium-Porphyrin Metal-Organic Framework (MPS-NPMOF) in the Treatment of Photoreceptor Degeneration. Int J Nanomedicine 2019, 14, 9763-9776.
Tao, H.; Chen, X.; Cao, H.; Zheng, L.; Li, Q.; Zhang, K.; Han, Z.; Han, Z. C.; Guo, Z.; Li, Z.; Wang, L. Mesenchymal Stem Cell-Derived Extracellular Vesicles for Corneal Wound Repair. Stem Cells Int 2019, 2019, 5738510.
Chen, Y.; Liu, W.; Shang, Y.; Cao, P.; Cui, J.; Li, Z.; Yin, X.; Li, Y. Folic acid-nanoscale gadolinium-porphyrin metal-organic frameworks: fluorescence and magnetic resonance dual-modality imaging and photodynamic therapy in hepatocellular carcinoma. Int J Nanomedicine 2019, 14, 57-74.
Wei Y, Wu Y, Zhao R, Zhang K, Midgley AC, Kong D, Li Z* and Zhao Q*. MSC-derived sEVs enhance patency and inhibit calcification of synthetic vascular grafts by immunomodulation in a rat model of hyperlipidemia. Biomaterials. 2019;204:13-24. Link
Cao H, Yue Z, Gao H, Chen C, Cui K, Zhang K, Cheng Y, Shao G, Kong D, Li Z*, Ding D* and Wang Y*. In Vivo Real-Time Imaging of Extracellular Vesicles in Liver Regeneration via Aggregation-Induced Emission Luminogens. ACS nano. 2019. 13, 3522-3533 Link
Zhao S, Xu J, Liu S, Cui K, Li Z and Liu N. Dppa3 in pluripotency maintenance of ES cells and early embryogenesis. J Cell Biochem. 2019;120:4794-4799.
Zhang Y, Wang D, Xu J, Wang Y, Ma F, Li Z and Liu N. Stat3 activation is critical for pluripotency maintenance. J Cell Physiol. 2019;234:1044-1051.
Sang H, Wang D, Zhao S, Zhang J, Zhang Y, Xu J, Chen X, Nie Y, Zhang K, Zhang S, Wang Y, Wang N, Ma F, Shuai L, Li Z and Liu N. Dppa3 is critical for Lin28a-regulated ES cells naiveprimed state conversion. J Mol Cell Biol. 2019; 11, 474-488.
Huang A, Liu D, Qi X, Yue Z, Cao H, Zhang K, Lei X, Wang Y, Kong D, Gao J, Li Z, Liu N and Wang Y. Self-assembled GFFYK peptide hydrogel enhances the therapeutic efficacy of mesenchymal stem cells in a mouse hindlimb ischemia model. Acta Biomater. 2019;85:94-105.
Chen Y, Liu W, Shang Y, Cao P, Cui J, Li Z, Yin X and Li Y. Folic acid-nanoscale gadolinium-porphyrin metal-organic frameworks: fluorescence and magnetic resonance dual-modality imaging and photodynamic therapy in hepatocellular carcinoma. Int J Nanomedicine. 2019;14:57-74.
He N, Kong Y, Lei X, Liu Y, Wang J, Xu C, Wang Y, Du L, Ji K, wang Q, Li Z* and Liu Q*. MSCs inhibit tumor progression and enhance radiosensitivity of breast cancer cells by down-regulating Stat3 signaling pathway. Cell Death & Disease. 2018;9:1026. Link
Zhang S, Liu Y, Zhang X, Zhu D, Qi X, Cao X, Fang Y, Che Y, Han Z-C, He Z-X, Han Z* and Li Z*. Prostaglandin E2 hydrogel improves cutaneous wound healing via M2 macrophages polarization. Theranostics. 2018; 8(19):5348-5361 (IF, 8.5) Link
Zhang K, Zhao X, Chen X, Wei Y, Du W, Wang Y, Liu L, Zhao W, Han Z, Kong D, Zhao Q, Guo Z, Han Z, Liu N, Ma F* and Li Z*. Enhanced Therapeutic Effects of MSC-derived Exosomes with an Injectable Hydrogel for Hindlimb Ischemia Treatment. ACS Applied Materials & Interfaces. 2018;10:30081-91. Link (IF, 8.0)
Tao H, Chen X, Wei A, Song X, Wang W, Liang L, Zhao Q, Han Z, Han Z, Wang X* and Li Z*. Comparison of Teratoma Formation between Embryonic Stem Cells and Parthenogenetic Embryonic Stem cells by Molecular Imaging. Stem Cell International. 2018;2018:7906531. Link
Luo X, Huang S, He N, Liu C, Chen Y, Liu Y, Mi X, Li N, Sun P, Li Z, Xiang R and Su W.. Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1b-Dependent Manner. BioMed Research International. 2018;2018:12.
Lim M, Wang W, Liang L, Han ZB, Li Z, Geng J, Zhao M, Jia H, Feng J, Wei Z, Song B, Zhang J, Li J, Liu T, Wang F, Li T, Li J, Fang Y, Gao J and Han Z. Intravenous injection of allogeneic umbilical cord-derived multipotent mesenchymal stromal cells reduces the infarct area and ameliorates cardiac function in a porcine model of acute myocardial infarction. Stem Cell Res Ther. 2018;9:129.
Liu Y, Song B, Wei Y, Chen F, Chi Y, Fan H, Liu N, Li Z, Han Z and Ma F. Exosomes from mesenchymal stromal cells enhance imatinib-induced apoptosis in human leukemia cells via activation of caspase signaling pathway. Cytotherapy. 2018. 20(2): 181–188, Link
He N, Chen X, Wang D, Xu K, Wu L, Liu Y, Tao H, Zhao Q, Cao X, Li Y, Liu N, Qi X, Han Z, Kong D, Yang J* and Li Z*. VE-Cadherin regulates the self-renewal of mouse embryonic stem cells via LIF/Stat3 signaling pathway. Biomaterials. 2018;158:34-43. (IF, 8.8) Link
Nie Y, Zhang K, Zhang S, Wang D, Han Z, Che Y, Kong D, Zhao Q, Han Z, He ZX, Liu N, Ma F and Li Z*. Nitric Oxide Releasing Hydrogel Promotes Endothelial Differentiation of Mouse Embryonic Stem Cells. Acta Biomater. 2017;63:190-199. IF, 6.319 Link
Mao D, Zhu M, Zhang X, Ma R, Yang X, Ke T, Wang L, Li Z*, Kong D and Li C. A macroporous heparin-releasing silk fibroin scaffold improves islet transplantation outcome by promoting islet revascularisation and survival. Acta Biomaterialia. 2017: 59:210-220. Link
Du W, Zhang K, Zhang S, Wang R, Nie Y, Tao H, Han Z, Liang L, Wang D, Liu J, Liu N, Han Z, Kong D, Zhao Q and Li Z*. Enhanced proangiogenic potential of mesenchymal stem cell-derived exosomes stimulated by a nitric oxide releasing polymer. Biomaterials. 2017, 133:70-81. Link (IF, 8.8)
Wang R, Zhang K, Tao H, Du W, Wang D, Huang Z, Zhou M, Xu Y, Wang Y, Liu N, Wang H and Li Z*. Molecular Imaging of Tumor Angiogenesis and Therapeutic Effects with Dual Bioluminescence. Current Pharmaceutical Biotechnology. 2017;18:1-1. IF, 2.459 Link
Liang L, Yue Z, Du W, Li Y, Tao H, Wang D, Wang R, Huang Z, He N, Xie X, Han Z, Liu N and Li Z*. Molecular Imaging of Inducible VEGF Expression and Tumor Progression in a Breast Cancer Model. Cell Physiol Biochem. 2017;42:407-415. IF, 5.104 Link
Wang D, Sang H, Zhang K, Nie Y, Zhao S, Zhang Y, He N, Wang Y, Xu Y, Xie X, Li Z* and Liu N*. Stat3 phosphorylation is required for embryonic stem cells ground state maintenance in 2i culture media. Oncotarget. 2017, 8:31227-31237. Link
Liang L, Li Z, Ma T, Han Z, Du W, Geng J, Jia H, Zhao M, Wang J, Zhang B, Feng J, Zhao L, Rupin A, Wang Y and Han ZC. Transplantation of human placenta derived mesenchymal stem cell alleviates critical limb ischemia in diabetic nude rat. Cell Transplant. 2017;26:45-61. IF, 3.0 Link
Lei X, Cai S, Chen Y, Cui J, Wang Y, Li Z and Li Y. Down-regulation of interleukin 7 receptor (IL-7R) contributes to central nervous system demyelination. Oncotarget. 2017; 8:28395-28407. Link
Zhang D-Y, Nie Y, Sang H, Suo J-J, Li Z-J, Gu W, Tian J-L, Liu X and Yan S-P. Three structurally related Copper complexes with two isomers: DNA/BSA binding ability, DNA cleavage activity and excellent cytotoxicity. Inorganica Chimica Acta. 2017;457:7-18. IF, 2.0 Link
Liu Y, Wang Z, Huang D, Wu C, Li H, Zhang X, Meng B, Li Z, Zhu T, Yang S and Sun W. LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling. Oncotarget. 2017;8:9513-9524. Link
Xianghe Song, Danni Liu, Jian Cui, Manqian Zhou, Hui Wang, Na Liu, Xin Qi, and Zongjin Li*. Identification of Stem-like Cells in Atrial Myxoma by Markers CD44, CD19 and CD45. Stem Cells International. 2016, 2016:2059584. Link IF, 3.54
Chi Y, Cui J, Wang Y, Du W, Chen F, Li Z, Ma F, Song B, Xu F, Zhao Q, Han Z and Han Z. Interferongamma alters the microRNA profile of umbilical cordderived mesenchymal stem cells. Mol Med Rep. 2016; 14:4187-4197. Link
Liu Y, Huang D, Wang Z, Wu C, Zhang Z, Wang D, Li Z, Zhu T, Yang S and Sun W. LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer. Sci Rep. 2016; 6:36050. Link
Liu D, Qi X, Li Q, Jia W, Wei L, Huang A, Liu K and Li Z. Increased complements and high‑sensitivity C‑reactive protein predict heart failure in acute myocardial infarction. Biomedical Reports. 2016; 5:761-5. Link
He N, Feng G, Li Y, Xu Y, Xie X, Wang H, Wang Y, Ou L, Pei X, Liu N*, Li Z*. Embryonic stem cell preconditioned microenvironment suppresses tumorigenic properties in breast cancer; Stem Cell Res Ther. 2016;7:95. Link IF, 4.211
Cai M, Shen R, Song L, Lu M, Wang J, Zhao S, Tang Y, Meng X, Li Z* and He Z-X*. Bone marrow mesenchymal stem Cells (BM-MSCs) improve heart function in swine myocardial infarction model through paracrine effects. Sci Rep. 2016;6:28250. Link
Liu N, Qi X, Han Z, Liang L, Kong D, Han ZC, Zhao S, He ZX*, Li Z*. Bone Marrow Is a Reservoir for Cardiac Resident Stem Cells. Sci Rep. 2016, 6: 28739 Link
Zhou XQ, Li Y, Zhang DY, Nie Y, Li ZJ, Gu W, Liu X, Tian JL and Yan SP. Copper complexes based on chiral Schiff-base ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis. Eur J Med Chem. 2016;114:244-56. Link IF, 4.519
Du WJ, Chi Y, Yang ZX, Li ZJ, Cui JJ, Song BQ, Li X, Yang SG, Han ZB and Han ZC. Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta. Stem Cell Res Ther. 2016;7:163. Link
Du W, Li X, Chi Y, Ma F, Li Z, Yang S, Song B, Cui J, Ma T, Li J, Tian J, Yang Z, Feng X, Chen F, Lu S, Liang L, Han ZB and Han ZC. VCAM-1(+) placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity. Stem Cell Res Ther. 2016;7:49. Link
Nie Y and Li ZJ*. Controlled nitric oxide release for tissue repair and regeneration. Turkish Journal of Biology. 2016;40:316-326. Link
Jia XH, Feng GW, Wang ZL, Du Y, Shen C, Hui H, Peng D, Li ZJ, Kong DL and Tian J. Activation of mesenchymal stem cells by macrophages promotes tumor progression through immune suppressive effects. Oncotarget. 2016; 7:20934-44. Link
Tao H, Han Z, Han ZC, Li Z*. Proangiogenic Features of Mesenchymal Stem Cells (MSCs) and Their Therapeutic Applications. Stem Cell International. 2016; 2016:1314709 Link
Feng G, Zhang J, Li Y, Nie Y, Zhu D, Wang R, Liu J, Gao J, Liu N, He N, Du W, Tao H, Che Y, Xu Y*, Kong D, Zhao Q*, Li Z*. IGF-1C Modified Hydrogel Enhances Cell Therapy for Acute Kidney Injury. J Am Soc Nephrol. 2016; 27: 2357-2369. (IF, 9.3) Recommended by Faculty 1000 with editorial, J Am Soc Nephrol 27: 2219–2221, 2016. F1000评价 Link
Du W, Tao H, Zhao S, He Z*, Li Z*. Translational Applications of Molecular Imaging in Cardiovascular Disease and Stem Cell Therapy. Biochimie, 2015;116:43-51 (IF, 3.2) Link
He N, Xu Y, Du W, Qi X, Wang Y, Feng G, Fan Y, Kong D, Han Z, Cheng Z, Wu JC, He Z, Li Z*. Extracellular matrix can recover the downregulation of adhesion molecules after cell detachment and enhance endothelial cell engraftment. Sci Rep, 2015, 5:10902 (IF, 5.078) Link
Yao X, Liu Y, Gao J, Yang L, Mao D, Stefanitsch C, Li Y, Zhang J, Ou L, Kong D, Zhao Q*, Li Z*. Nitric oxide releasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction. Biomaterials, 2015, 60:130-140 (IF, 8.8) link
Zhao Q, Li Z*. Angiogenesis. BioMed Research International, 2015. 2015:135861 (IF, 2.7) Link
Wang L, Su W, Du W, Xu Y, Wang L, Han Z, Zheng G, Li Z*. Gene and microRNA Profiling of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Stem Cell Rev, 2015, 11:219-27 (IF, 3.214) Link
Liu C, Li Z, Wang L, Tong L, He N, Chen Y, Liu Y, Wu Z, Sun P, Xiang R, Ren G*, Su W*. Activating Transcription Factor 4 Promotes Angiogenesis of Breast Cancer through Enhanced Macrophage Recruitment. BioMed Research International, 2015, 2015:974615 (IF, 2.7) Link
Zhang X, Zhu D, Wei L*, Zhao Z, Qi X, Li Z*, Sun D*. OSM enhances angiogenesis and improves cardiac function after myocardial infarction. BioMed Research International, 2015, 2015: 317905 (IF, 2.7) Link
Wang Y, Feng G, Wang J, Zhou Y, Liu Y, Shi Y, Zhu Y, Lin W, Xu Y, Li Z*. Differential effects of tumor necrosis factor-alpha on matrix metalloproteinase-2 expression in human myometrial and uterine leiomyoma smooth muscle cells. Hum Reprod. 2015;30:61-70 (IF, 4.585) Link
Huang M, Du W, He ZX, Li Z*. Molecular imaging of angiogenesis in cardiovascular diseases. J Mol Biol & Mol Imaging. 2015; 2(1): 1012. Link
Wang Y, Li M, Xu Y, He N, Leng L, Li Z*. Tumor necrosis factor-alpha regulates matrix metalloproteinase-2 expression and cell migration via erk pathway in rat glomerular mesangial cells. Cell Biol Int. 2014; 38, 1060-1068 (IF, 1.635) Link
Zhou Y, Ren Y, Cui L, Li Z, Zhu Y, Lin W, Wang Y. Differential expression of caveolin-1 in human myometrial and uterine leiomyoma smooth muscle. Am J Obstet Gynecol. 2014; 211, 496 e491-496 e413 (IF, 3.973) Link
Wang Y, Li Z*. Traceable therapeutic strategy for treatment of breast cancer with mesenchymal stem cells (MSCs). Can Cell Microenviron. 2014;1:125-128 Link
Zhao Q, Tong L, He N, Feng W, Leng L, Su W, Xu Y, Wang Y, Xiang R, Li Z*. IFN-g mediate graft-versus-breast cancer effects via enhancing cytotoxic T lymphocytes activation. 2014, Exp Ther Med.2014, 8:347-354 (IF, 0.941) Link
He N, Zhang L, Cui J, Li Z*. Bone marrow vascular niche: Home for hematopoietic stem cells. Bone Marrow Research. 2014;2014:1-8 Link
Leng L, Wang Y, He N, Wang D, Zhao Q, Feng G, Su W, Xu Y, Han Z, Kong D, Cheng Z, Xiang R, Li Z*. Molecular Imaging for Assessment of Mesenchymal Stem Cells Mediated Breast Cancer Therapy. Biomaterials, 2014, 35:5162-70 （IF, 8.8）Link
Fang F, Wasserman SM, Torres-Vazquez J, Weinstein B, Cao F, Li Z, Wilson KD, Yue W, Wu JC, Xie X and Pei X. The role of Hath6, a novel shear stress-responsive transcription factor, in endothelial differentiation and function modulation. J Cell Sci. 2014, 127:1428-1440 (IF, 5.325) Link
Liu J*, Liu JJ, Chu L, Tong L, Gao H, Yang C, Wang D, Shi L, Kong D, Li Z*. Synthesis, Biodistribution, and Imaging of PEGylated-Acetylated Polyamidoamine Dendrimers. J Nanosci Nanotech. 2014, 14(5): 3305-12. (IF, 1.339) Link
Wang L, Wang Y, Li, Z*. Advances in Nanoparticle-Based Tumor Theranostics with Molecular Imaging. Curr Pharm Biotechnol, 2013, 14(7), 683-92, PMID 24372235 (IF, 2.511) Link
Feng G, Mao D, Che Y, Su W, Wang Y, Xu Y, Fan Y, Zhao H, Kong D, Xu Y, Li Z*. The Phenotypic Fate for Bone Marrow-Derived Stem Cells in Acute Kidney Injury. Cellular Phys Biochem, 2013, 32:1517-1527. (IF, 3.55) Link
Chen IY, Gheysens O, Li Z, Rasoonly JA, Wang Q, Paulmurugan R, Rosenberg J, Rodriguez-Porcel R, Willmann JK, Wang DS, Contag CH, Robbins RC, Wu JC, Gambhir SS. Noninvasive imaging of hypoxia-inducible factor-1a gene therapy for myocardial ischemia. Hum Gene Ther Methods. 2013, 24(5): 279-88 Link (IF, 1.641)
Bai N, Zhang C, Liang N, Zhang Z, Chang A, Yin J, Li Z, Luo N, Tan X, Luo N, Luo Y, Xiang R, Li X, Reisfeld RA, Stupack D, Lv D, Liu C. Yes-associated protein (yap) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53. Cancer Biol Ther. 2013;14:511-520 Link (IF, 3.63)
Jia XH, Lu H, Li C, Feng GW, Yao XP, Mao LN, Ke TY, Che YZ, Xu Y, Li ZJ*, Kong DL*. Human embryonic stem cells-derived endothelial cell therapy facilitates kidney regeneration by stimulating renal resident stem cell proliferation in acute kidney injury. Chin Sci Bull 2013;58:2820-2827 Link (IF, 1.365)
Zhang J, Jia X, Xu Z, Ding F, Zhou X, Fu H, Liu Y, Ou L, Li Z, Kong D. Improved Mesenchymal Stem Cell Survival in Ischemic Heart Through Electroacupuncture. Chin J Integr Med. 2013, 19(8): 573-81. Link. (IF, 1.401)
Liu Y, Ye X, Mao L, Cheng Z, Yao X, Jia X, Mao D, Ou L, Li Z, Che Y, Liu N, Steinhoff G, Liu L, Kong D. Transplantation of parthenogenetic embryonic stem cells ameliorates cardiac dysfunction and remodeling after myocardial infarction. Cardiovas Res. 2012, 97(2): 208-18.Link (IF, 5.808)
Su W, Wang L, Zhou M, Tong L, Liu Z, Hu S, Liu F, Liu Y, Yan F, Kong D, Han Z, WuJC, Xiang R, Li Z*. Human Embryonic Stem Cell-derived Endothelial Cells as Cellular Delivery Vehicles for Targeting Therapy of Breast Cancer. Cell Transplant. 2013;22(11):2079-90. PMID: 23067802 Link (IF, 3.57)
Jia X, Xie X, Feng G, YaoX, Lü H, Mao L, Zhao Q, Che Y, Han Z, XuY, Li Z*, Kong D*. Bone marrow-derived cells can acquire renal stem cells properties and ameliorate ischemia-reperfusion induced acute renal injury. BMC Nephrol. 2012, 13: 105. PMID: 22963129 (IF, 1.52) Link
Daadi MM, Hu S, Klausner J, Li Z, Sofilos M, Sun G, Wu JC, Steinberg GK. Imaging Neural Stem Cell Graft-Induced Structural Repair in Stroke. Cell Transplant. 2013; 22(4): 881-892. PMID: 23044338 (IF, 3.57) Link
Lu D, Chen S, Tan X, Li N, Liu C, Li Z, Liu Z, Stupack DG, Reisfeld RA, Xiang R. Fra-1 Promotes Breast Cancer Chemosensitivity by Driving Cancer Stem Cells from Dormancy. Cancer Res, 2012, 72(14): 3451-6. Link (IF, 9.284)
Wang L, Su W, Liu Z, Zhou M, Chen S, Chen Y, Lu D, Liu Y, Yan F, Zheng Y, Han Z, Kong D, WuJC, Xiang R, Li Z*. CD44 Antibody Targeted Liposomes for Molecular Imaging and Therapy of Hepatocellular Carcinoma. Biomaterials. 2012, 33(20): 5107-5114 Link (IF, 8.312)
Wang L, Chen S, Zhang M, Chen Y, Su W, Liu Y, Lu D, Li S, Yang Y, Li Z, Qu P, Hu H, Xiang R. Legumain Serves as a Biomarker for the Diagnosis and Prognosis of Human Ovarian Cancer. J Cell Biochem. 2012, 113(8): 2679-86. Link (IF, 3.368)
Zhou M, Wang L, Su W, Tong L, Liu Z, Liu Y, Yan F, Zheng Y, Zhao H, Xiang R, Li Z*. Assessment of Therapeutic Efficacy of Liposomal Nanoparticles Mediated Gene Delivery by Molecular Imaging for Cancer Therapy. J Biomed Nanotechnol. 2012, 8(5): 742-750. Link (IF, 7.578)
Feng G, Cui J, Zheng Y, Han Z, Xu Y*,Li Z*. Identification, Characterization and Biological Significance of Very Small Embryonic-Like Stem Cells (VSELs) in Regenerative Medicine. Histol Histopathol. 2012, 27(7): 827-833. PMID: 22648539 Link. (IF, 2.236)
Zhang Z, Yin J, Zhang C, Liang N, Bai N, Chang A, Liu Y, Li Z, Tan X, Li N, Lv D, Xiang R, Tian Y, Liu C. Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma. Cancer Biol Ther, 2012, 13(6) 435-442. Link (IF, 3.63)
Hu S, Huang M, Nguyen P, Gong Y, Li Z, Jia F, Lan F, Liu J, Nag D, Robbins RC, Wu JC. Novel MicroRNA Pro-survival Cocktail for Improving Engraftment and Function of Cardiac Progenitor Cell Transplantation. Circulation. 2011, 124: S27-S34. Link (IF, 14.948) (Top 3 advances in AHA Basic Cardiovascular Sciences in 2011)
Li Z, Hu S, Ghosh Z, Han Z, Wu JC. Functional Characterization and Expression Profiling of Human Induced Pluripotent Stem Cell- and Embryonic Stem Cell-Derived Endothelial Cells. Stem Cell Dev. 2011, 20(10): 1701-1710. Link (IF, 4.202)
Su W, Zhou M, Zheng Y, Fan Y, Han Z, Kong D, Zhao RC, Wu JC, Xiang R*, Li Z*. Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation. J Cell Biochem. 2011, 112: 840-848. Link. (*Correspondence author) (IF, 3.368)
Wang Y, Wang Yanming, Wang L, Che Y, Li Z*, Kong D*. Preparation and evaluation of magnetic nanoparticles for cell labeling. J Nanosci Nanotechnol. 2011, 11: 3749-3756. Link (IF, 1.339)
Xie X, Hiona A, Lee A, Cao F, Huang M, Li Z, Cherry A, Pei X, Wu JC. Effects of Long Term Culture on Human Embryonic Stem Cell Aging. Stem Cell Dev. 2011; 20(1): 127-38. Link (IF, 4.202)
Hu S, Huang M, Li Z, Jia F, Ghosh Z, Lijkwan M, Sun N, Fasanaro P, Wang X, Martelli R, Robbins RC, Wu JC. MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease. Circulation. 2010, 122:S124-S131. Link. (IF, 14.948)
Wilson KD, Sun N, Huang M, Zhang WY, Lee AJ, Li Z, Wang SX, Wu JC. Effects of Ionizing Radiation on Self Renewal and Pluripotency of Human Embryonic Stem Cells. Cancer Research. 2010, 70(13): 5539-48. Link (IF, 9.284)
Huang NF, Niiyama H, Peter C, De A, Natkunam Y, Fleissner FA, Li Z, Rollins M, Wu JC, Gambhir SS, Cooke JP. Embryonic Stem Cell-Derived Endothelial Cells Incorporate into the Ischemic Hindlimb and Restore Perfusion. Arterioscler Thromb Vasc Biol. 2010, 30:915-922. Link (IF, 5.533)
Jia F, Wilson KD, Sun N, Gupta DM, Huang M, Li Z, Kay MA, Longaker MT, Wu JC. A Simple Non-viral Minicircle Vector for Deriving Human iPS Cells. Nature Methods. 2010, 7(3): 197-199. Link. (IF, 25.953)
DaadiDM, DavisA, Arac A, Li Z, MaagAL, Batnagar R, SunG, WuJC, Steinberg GK. Human Neural Stem Cell Grafts Modify Microglial Response and Enhance Axonal Sprouting In Neonatal Hypoxic-Ischemic Brain Injury. Stroke. 2010, 41(3): 516-23. Link (IF, 6.018) (selected by F1000)
Li Z, Wilson KD, Smith B, Kraft D, Jia F, Xie X, Huang M, Hoyt G, Chu P, Robbins RC, Weissman IL, Gambhir SS, Wu JC. Functional and Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction. PLoS ONE. 2009, 4(12): e8443. Link (IF, 4.4)
Yu J, Huang NF, Wilson KD, Velotta JB, Huang M, Li Z, Robbins RR, Cooke JP, Wu JC. nAChRs Mediate Human Embryonic Stem Cell-Derived Endothelial Cells: Proliferation, Apoptosis, and Angiogenesis. PLoS ONE. 2009, 4(9): e7040. Link (IF, 3.534)
Huang M, Chen ZY, Jia F, Li Z, Kay MA, Wu JC. Novel minicircle vector for cell based gene therapy in murine myocardial infarction. Circulation. 2009, 120:S230-S237 Link (IF, 14.948)
Daadi DM, Li Z, Arac A, GrueterBA, Sofilos M, Malenka RC, Wu JC, Steinberg GK. Molecular and Magnetic Resonance Imaging of Human Embryonic Stem Cell-Derived Neural Stem Cell Grafts in Ischemic Rat Brain. Molecular Therapy. 2009, 17(7): 1282–1291. Link. (IF, 6.425)
Li Z, Lee A, Huang M, Chung J, Chu P, Yang P, Rosenberg J, Robbins RC, Wu JC. Imaging Survival and Function of Transplanted Cardiac Stem Cells. J Am Coll Cardiol. 2009, 53(14): 1229–40. Link (IF,15.343)
Li Z*, Han Z, Wu JC*. Transplantation of Human Embryonic Stem Cell-Derived Endothelial Cells for Vascular Diseases. J Cell Biochem. 2009, 106:194-199. (Journal cover, invited review) Link (IF, 3.368)
Xie X, Chan KS, Cao F, Hang M, Li Z, Lee A, Weissman I, Wu JC. Imaging of STAT3 Signaling Pathway During Mouse Embryonic Stem Cell Differentiation. Stem Cell Dev. 2009; 18(2):205-14. Link (IF, 4.202)
Huang M, Chan D, Jia F, Xie X, Li Z, Robbins RC, Chen X, Giaccia A, Wu JC. Short Hairpin RNA Interference Therapy for Ischemic Heart Disease. Circulation.2008; 118: s226-233. Link (IF, 14.948)
*Wilson KD, *Li Z, Wager R, Yue P, Tsao P, Nestorova G, Huang M, Hirschberg D, Yock PG, Quertermous D, Wu JC. Transcriptome alteration in the diabetic heart by rosiglitazone: Implications for cardiovascular mortality. PLoS ONE. 2008, 3(7): e2609. (*Co-first author) Link (IF, 3.534)
Li Z, Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang PC, Wu JC. Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. Stem Cells. 2008, 26(4): 864-873. Link (IF, 7.133)
Li Z, Wu JC, Sheikh AY, Kraft D, Cao F, Xie XY, Patel M, Gambhir SS, Robbins RC, Cooke JP, Wu JC. Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation.2007; 116: I46-I54. Link (IF, 14.948)
Xie X, Cao F, Sheikh AY, Li Z, Connolly AJ, Pei X, Li RK, Robbins RC, Wu JC. Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function. Cloning and Stem Cells. 2007; 9(4): 553-567 Link (IF, 2.9)
Cao F, Drukker M, Lin S, Sheikh AY, Xie X, Li Z, Connolly AJ, Weissman IL, Wu JC.. Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. Cloning and Stem Cells. 2007; 9(1): 107-17. Link (IF, 2.9)
Lin S, Xie X, Patel MR, Yang YH, Li Z, Cao F, Gheysens O, Zhang Y, Gambhir SS, Rao JH, Wu JC. Quantum dot imaging for embryonic stem cells. BMC Biotechnol. 2007; 7(1): 67 Link (Featured in Nanowerk). (IF, 2.592)
Chang GY, Cao F, Krishnan M, Huang M, Li Z, Xie X, Sheikh AY, Hoyt G, Robbins RC, Hsiai T, Schneider MD, Wu JC. Positron emission tomography imaging of conditional gene activation in the heart. J Mol Cell Cardiol. 2007; 43(1):18-26. (Journal cover) Link (IF, 5.218)
Xiao Z, Wang Y, Lu L, Li Z, Peng Z, Han Z, Hao Y. Anti-angiogenesis effects of meisoindigo on chronic myelogenous leukemia in vitro. Leuk Res.2006; 30(1): 54-9. Link (IF, 2.692)
Li ZJ, Wang ZZ, Zheng YZ, Xu B, Yang RC, Scadden DT, Han ZC. Kinetic expression of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) during embryonic stem cell differentiation. J Cell Biochem. 2005; 95(3): 559-570. Link (IF, 3.368)
Yang C, Zhang ZH, Li ZJ, Yang RC, Qian GQ, Han ZC. Enhancement of neovascularization with cord blood CD133+ cell-derived endothelial progenitor cell transplantation. Thrombosis Haemostasis. 2004; 91(6): 1202-1212. Link (IF, 5.76)

Book/Chapters

Yizhou Zheng, Deling Kong and Zongjin Li* (2011). Non-invasive Imaging of Human Embryonic Stem Cells Derived Endothelial Cells Using Reporter Genes, Methodological Advances in the Culture, Manipulation and Utilization of Embryonic Stem Cells for Basic and Practical Applications, Craig Atwood (Ed.), ISBN: 978-953-307-197-8, InTech, (*correspondence author) Link
Hu S, Lavinghousez P, Li Z, Wu JC (2011). Differentiation of endothelial cells from hES cells and hiPS cells., Human Embryonic and Induced Pluripotent Stem Cells, Ye, Kaiming; Jin, Sha (Eds.) ISBN 978-1-61779-266-3, Humana Press. Link
Tong L, Zhao H, He Z, Li Z (2012). Current Perspectives on Molecular Imaging for Tracking Stem Cell Therapy "Medical Imaging in Clinical Practice", Erondo OF (Eds) ISBN 980-953-307-710-4. InTech.
Weijun Su, Liang Leng, Zhongchao Han, Zuoxiang He, and Zongjin Li* (2013). Bioluminescence Imaging of Human Embryonic Stem Cells-Derived Endothelial Cells for Treatment of Myocardial Infarction. ISBN 978-1-62703-558-3 Humana Press.
Su W, Xiang R, Li Z*. “Liposomal Nanoparticles as Targeted Drug Delivery Vehicles in Cancer Therapy" in "Recent Developments in Biotechnology", Ashok Kumar (Eds), ISBN 1-62699-025-5, Studium Press LLC, USA
He N, Li Z*, Molecular Imaging: The Key to Advancing Stem Cell Therapy, Stem Cells: Basics and Clinical Translation, 2015, DOI: 10.1007/978-94-017-7273-0_9
Zhang S, Nie Y, Tao H and Li Z. Hydrogel-Based Strategies for Stem Cell Therapy. In: V. K. Thakur and M. K. Thakur, eds. Hydrogels: Springer Singapore; 2018: 87-112.
Shen J, Tao H and Li Z. Current View on Hematopoiesis and Beyond Stem Cells in Clinical Practice and Tissue Engineering: InTech; 2018: 23-30.
韩忠朝, 李宗金主译，Meshore E， Plath K著。干细胞的细胞生物学，科学出版社， 2014年6月。ISBN 978-7-03-040867-9
韩忠朝主编，李宗金、韩之波副主编。围产期干细胞，科学出版社, 2014年1月。ISBN 978-7-03-039394-4
Han, Z. C.; Takahashi, T. A.; Han, Z.; Li, Z. Perinatal Stem Cells. Springer: Singapore, 2019; p VI, 173. ISBN 978-981-13-2702-5
Zhang, K.; Li, Z. Molecular Imaging of Therapeutic Effect of Mesenchymal Stem Cell-Derived Exosomes for Hindlimb Ischemia Treatment. In Methods Mol Biol, Humana Press: 2019.

Nankai University School of Medicine
Tianjin 300071
China